Legendary trainer Sir Henry Cecil died on Tuesday morning at the age of 70 following a long battle with stomach cancer.
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Champion trainer 10 times and responsible for 25 British Classic winners, the master of Warren Place in Newmarket was also the leading handler by some way at Royal Ascot with a record 75 successes.
In 2008, Cecil married his third wife, his one-time secretary Jane McKeown. He is survived by two children, Katie and Noel, from his first marriage, and son Jake from his second marriage.
Lady Cecil has been granted a temporary training licence by the British Horseracing Authority, with runners declared for Newbury, Nottingham and Yarmouth on Thursday.
Photo Galleries/Sir Henry Cecil
A pictorial look at the glittering career of legendary trainer Sir Henry Cecil, who has died at the age of 70
Knighted by the Queen in 2011, Cecil's later years saw him fight cancer but were illuminated by the great Frankel, officially the best horse in the world and unbeaten in 14 starts before retirement at the end of last season.
Frankel carried the colours of Cecil's great patron Prince Khalid Abdullah, owner of Juddmonte Farms.
"It is with immense sadness that we have learnt that Sir Henry Cecil lost his long battle with cancer this morning," said a statement onwww.juddmonte.com.
"Henry has been both a longstanding friend of Prince Khalid's and a wonderful trainer for Juddmonte and beyond.
"Our thoughts today are with Jane and all his family, and his loyal staff at Warren Place."
Frankel was ridden in all his races by Tom Queally, Cecil's first jockey in recent years.
He told Racing UK: "Every other trainer aspires to be like him and no other trainer will come close.
"He really excelled with Frankel. He made all he right calls and all the right choices with him.
"He retired unbeaten and that was his jewel in the crown. Racing has lost a real gem."
American Steve Cauthen enjoyed six highly successful years as stable jockey, including many Classic triumphs and the Triple Crown success of the filly Oh So Sharp in 1985.
"It's a great loss to the sport and to everybody who knew him. He was such a great guy - different, special, a genius and we had six great years together," he said.
"The first year we had an amazing run when Slip Anchor won the Derby and Oh So Sharp won the Triple Crown for fillies.
"He had a great sense of humour. He was a super intelligent guy and really knew how to place his horses.
"The way he trained was great and the way he placed them was fantastic. He was a special trainer.
"He did a perfect job in making Frankel the horse he was."
An emotional Pat Eddery remembered his time riding for the master of Warren Place.
"He was a great trainer, he was a genius and I was very fortunate to have ridden for him and it's just really sad," he told At The Races.
"He was never overpowering. He was quite an easy person to get on with.
"He just trained some great horses. He's gone through some bad times, came back and did it again."
Six-times champion Kieren Fallon, another of the elite band of Cecil stable jockeys, described him as a "legend".
"He was a legend. My first year with him, I was champion jockey. We had a great rapport and he will be sadly missed," he told Sky Sports News.
"We won the Derby with Oath, the Guineas with Sleepytime, we had a lot of great success.
"I think Frankel will be on everybody's mind, the way he trained that horse, one of the greatest horses we've ever seen - we'll not see another one like him."
Like Cecil, Sir Michael Stoute has been champion trainer 10 times and paid the ultimate tribute by describing him as the best trainer the UK has ever had.
"I do not believe this country has ever produced a better trainer than Henry," said the Freemason Lodge handler.
"I know there has never been one so loved.
"And then there was his toughness and courage which had to be seen to be believed as he continued to supervise the training of his horses. Some man."
Trainer Harry Dunlop was Cecil's godson and spent three years at Warren Place.
"It's a massive loss for racing as a whole. We saw last year and the year before with Frankel how incredible he was as a trainer," he said.
"I think he was an incredible trainer of a very good horse, the planning and patience with his two-year-olds were his strengths, and then knowing the correct race to go for.
"I was there when things weren't going well, but the incredible thing is that he brought it back up to be one of the most successful yards in the and again. Not many do that."
Racing remembered Cecil with a minute's silence before each of Tuesday's four meetings.
Sir Henry Cecil factfile:
Full name: Sir Henry Richard Amherst Cecil.
Born: January 11, 1943 in Aberdeen.
Apprenticeship: Assistant to stepfather Sir Cecil Boyd-Rochfort 1964-8.
First trainer's licence: 1969.
Champion trainer: 1976, 1978-9, 1982, 1984-5, 1987-8, 1990, 1993. Set a record of 180 winners in 1987 (broken by Richard Hannon in 1993)
Derby winners: Slip Anchor 1985, Reference Point 1987, Commander In Chief 1993, Oath 1999.
Other British Classic winners: 1000 Guineas: One In A Million 1979, Fairy Footsteps 1981, Oh So Sharp 1985, Bosra Sham 1996, Sleepytime 1997, Wince 1999.
2000 Guineas: Bolkonski 1975, Wollow 1976, Frankel 2011.
Oaks: Oh So Sharp 1985, Diminuendo 1988, Snow Bride 1989, Lady Carla 1996, Reams Of Verse 1997, Ramruma 1999, Love Divine 2000, Light Shift 2007
St Leger: Light Cavalry 1980, Oh So Sharp 1985, Reference Point 1987, Michelozzo 1989
Irish Classic winners: 1000 Guineas: Cloonagh 1973, Derby: Old Vic 1989, Commander In Chief 1993, Oaks: Diminuendo 1988, Alydaress 1989, Ramruma 1999
French Classic winners: Derby: Old Vic 1989, Oaks: Indian Skimmer 1987, Rafha 1990
King George VI And Queen Elizabeth Diamond Stakes winners: Reference Point 1987, Belmez 1990, King's Theatre 1994
Other information: Cecil has trained more Royal Ascot winners than anyone else. His total of 75 includes success every year from 1974 to 2002, with the exception of 1996. He won the Racing Post Trophy at Doncaster nine times between 1975 and 1993 and the May Hill Stakes at the same track eight times from 1984 to 1996
He was awarded a Knighthood in the Queen's 2011 Birthday Honours List for his services to horse racing.